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03-30-2025, 09:08 PM
(This post was last modified: 03-30-2025, 09:09 PM by Modafinil Modvigil.)
Le nom gГ©nГ©rique du modafinil est (S)-(diphГ©nylmГ©thyl) (2-benzyl-2-morpholinylГ©thyl) Г©ther. Le modafinil aide Г©galement les personnes aux prises avec la somnolence diurne due Г diverses autres causes. Le modafinil est utilisГ© pour traiter la somnolence diurne excessive chez les personnes atteintes de narcolepsie et de troubles du sommeil liГ©s au travail postГ©.
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Le modafinil semble agir en agissant sur la dopamine et en modulant les zones du cerveau impliquГ©es dans le cycle du sommeil. Il agit en augmentant le nombre de neurones dopaminergiques actifs dans le cerveau, provoquant une augmentation temporaire de l'Г©veil. Bien que le modafinil puisse ГЄtre dГ©tectГ© dans le sang, il n'est pas activement transportГ© dans le cerveau.
Il faut conseiller aux personnes pesant plus de 180 kg (400 lb) de prendre 400 mg deux fois par jour. La N-acГ©tylphГ©nylhydrazine est un agoniste inverse partiel des rГ©cepteurs de la sГ©rotonine dans le cerveau. Le modafinil, Г©galement connu sous le nom de Provigil aux Г‰tats-Unis, est un mГ©dicament d'ordonnance approuvГ© pour le traitement de la somnolence diurne excessive associГ©e Г la narcolepsie ou aux troubles du travail postГ©. Il affecte les neurotransmetteurs et les rГ©cepteurs du cerveau impliquГ©s dans la fonction de la dopamine (DA), de l'adГ©nosine et de l'acide gamma-aminobutyrique (GABA), se liant spГ©cifiquement au transporteur DA (DAT), au rГ©cepteur de l'adГ©nosine A2A et Г la sous-unitГ© GABA О±.
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Cible importante des mГ©dicaments anticonvulsivants, tels que le phГ©nobarbital, l'effet du modafinil protГЁge le cerveau des dommages au dГ©but de la crise. Le modafinil semble augmenter le niveau de dopamine dans le cerveau, en particulier dans le cortex prГ©frontal. Le modafinil Г©tait commercialisГ© en France sous le nom d'Alertec et aux Г‰tats-Unis sous le nom de Ritalin. Le modafinil est gГ©nГ©ralement bien tolГ©rГ©, mais il peut provoquer des effets secondaires tels que des maux de tГЄte, des troubles du sommeil, des problГЁmes de concentration et une augmentation de l'appГ©tit.
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05-27-2025, 02:19 AM
(This post was last modified: 05-27-2025, 03:12 AM by FrankJScott.)
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